Clinical Diagnostics

Development of laboratory diagnostics requires understanding of biomedical technology, deep clinical knowledge, and epidemiology of affected populations. Our lab aims to encompass each of these facets to generate real-world analytical test performance evaluations to guide clinical/public health practice and inform industry of their successes and pitfalls.

To date, our research has primarily focused on COVID-19 and Chagas disease serology. Major findings related to COVID-19 include early reports of SARS-CoV-2 serokinetics and relationship to disease severity. Our studies related to Chagas disease have demonstrated differential serological reactivity to commercial assays by region of birth throughout Latin America, suggesting host-parasite biology affects test performance.